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In this study we used
2018-11-02
In this study we used dermal fibroblasts derived from three different patients with distinct mutations in the TAZ1 gene (Houtkooper et al., 2009) and generated BTHS patient-specific iPSCs. We fully characterized them in terms of pluripotency both in vitro and in vivo. Similar to human ESCs, all gene
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The following are the supplementary data related to this art
2018-11-02
The following are the supplementary data related to this article. Author contribution Acknowledgment We thank Dr. Donald Vander Griend for providing CD133 cDNA, Dr. Oh-Joon Kwon and Ms. Li Zhang for technical help, the technical support by the Cytometry and Cell Sorting Core at Baylor College
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Our findings directly interface with the role of
2018-11-02
Our findings directly interface with the role of CXCL12 (SDF1)/CXCR4 signaling in adult HSPC migration: CXCL12 levels increase in response to stress and inflammation, and influence HSPC mobilization and extravasation within the adult BM (Dar et al., 2006). As hematopoietic niches are hypoxic during
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buy SGI1776 It is easy to see
2018-11-02
It is easy to see that the free constants U1, U2, … correspond to the potentials of a lesser degree, homogeneous in Euler\'s sense. These constants, except for the leading coefficient U0, can be set equal to zero without loss of generality. As a result, we can construct a set of linearly independent
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To our knowledge this is the
2018-11-02
To our knowledge, this is the first study to empirically test the claim that flexicurity policies have the capacity to attenuate the adverse health consequences of temporary employment across a large sample of advanced capitalist countries. Prior studies have challenged the notion that flexicurity c
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Given the evidence of interactions between non organizationa
2018-11-02
Given the evidence of interactions between non-organizational religious coping (asking others for prayer, and praying for self) with both individual and composite neighborhood quality indicators, we present the stratified parameter estimates (Tables 3 and 4, respectively). Among women who asked for
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Our study focuses on urban
2018-11-02
Our study focuses on urban governance that involves policies of local governments and provision of public goods and services. In accordance with federal and state authorities, many local agencies are established primarily at the county level. The delegation of authority to local governments, especia
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br Results Table presents basic descriptive information of o
2018-11-02
Results Table 1 presents basic descriptive information of our data. The estimates are presented first for all tracts, then for rural and urban tracts separately, with F-test p-values for testing rural-urban differences. Average marginal effects from multivariate fractional logit regression estim
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Most of the literature that explicitly include measures of
2018-11-02
Most of the literature that explicitly include measures of spouses’ resources examine mortality and do not account for the fact that illnesses may affect couples differently depending on spouses’ resources, cf. Monden et al. (2003) and Monden (2007). Our contribution to the literature is thus threef
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In the present data the prevalence
2018-11-01
In the present data, the prevalence of the morning type was low (N=47, 8.9%). The proportion of the intermediate type was the highest (N=298, 54.5%), followed by evening type (N=194, 35.0%). The genders were equally represented in the chronotypes, Pearson χ2(2)=1.79, n.s. The results of the analysi
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To assess whether cytochrome C release could
2018-11-01
To assess whether cytochrome C release could also be detected in the supernatant of rxr receptor exposed to different therapeutic agents, the MCF7 cells expressing Her2 were treated with drugs targeting this receptor (Trastuzumab with and without T-DM1). The responses shown in Fig. 2 show similarit
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br Conclusion The parameters of the shutter
2018-11-01
Conclusion The parameters of the shutter perforation width S, shutter thickness t, sense electrode width E, and shutter to electrode gap g were studied in relation to each other and with respect to the total shutter perforation repetition period L. It is found that shutter thickness and gap spaci
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br Consideraciones finales La intensidad migratoria y los
2018-11-01
Consideraciones finales La intensidad migratoria y los lugares de destino evidencian la falta de oportunidades laborales y como consecuencia la necesidad de aceptar empleos lejanos, que Erlotinib Hydrochloride pesar de su inestabilidad y salarios bajos, siguen representando un magro sustituto. Si
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br Introduction Neurofibromin Merlin NF is a
2018-11-01
Introduction Neurofibromin 2 (Merlin, NF2) is a tumour suppressor protein expressed during embryonic development and thereafter (Gronholm et al., 2005). In adults, significant levels of expression are found in Schwann and meningeal cells, nerve and lens (Claudio et al., 1997; Sakuda et al., 1996;
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br In this issue of Fu and colleagues investigated
2018-11-01
In this issue of , Fu and colleagues investigated the association between three BRCA1-associated RING domain protein 1 () gene single nucleotide polymorphisms (SNPs) and nephroblastoma susceptibility (). Based on the study conducted in a southern Chinese population consisting of 145 cases and 531
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