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The dorsal horn of the spinal cord shows a high
2022-07-13

The dorsal horn of the spinal cord shows a high density of Ca2+-permeable AMPA receptors, particularly in the superficial spinal laminae (laminae I and II), where primary afferents carrying nociceptive and thermoreceptive inputs terminate and synapse on spinal second-order neurons (Engelman et al.,
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NPI-0052 br Acknowledgements This research was funded by Min
2022-07-13

Acknowledgements This research was funded by Ministry of Education Malaysia (MOE), and supported by the Department of Nutrition, Exercise & Sports, Department of Drug Design, University of Copenhagen, Denmark and Universiti Malaysia Pahang (UMP), Malaysia. HPLC equipment used for high-resolution
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br Materials and methods br Results Unitary currents of Gard
2022-07-13

Materials and methods Results Unitary currents of Gardos WIN 18446 were identified by their conductance value, inward rectification, voltage independence of open probability, kinetics and Ca2+-sensitivity, all features which have been described elsewhere [8], [13], [20], [23], [24], [25], [26
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GHSR A s have high levels
2022-07-13

GHSR-1A's have high levels of constitutive activity and recent investigations show that constitutively active GHSR-1As in the absence of ligand (ghrelin) binding can have effects on feeding and energy balance (Mear et al., 2013, Petersen et al., 2009). Furthermore, GHSR-1As are capable of dimerizing
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Liver is the house for a variety of
2022-07-12

Liver is the house for a variety of xenobiotic-metabolizing Zinc protoporphyrin IX that produce reactive oxygen species as well as reactive metabolites (Johansson et al., 2009; Noh et al., 2017; Puntarulo and Cederbaum, 1998). When the enzymes act upon pre- or pro-haptens, the chemicals would be act
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br Introduction The brain contains abundant fatty acids whic
2022-07-12

Introduction The brain contains abundant fatty acids, which serve as constituents of membranes and as an energy source. In addition, fatty acids and their metabolites contribute to signal transduction between neurons or neurons and glial cells, suggesting that fatty acids play a crucial role in d
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br Significance Metabolites present in the extracellular env
2022-07-12

Significance Metabolites present in the extracellular environment can potently modulate cellular phenotypes and potentially serve as therapeutics for various diseases. Ferroptosis is a non-apoptotic cell death process characterized by the generation of toxic lipid reactive oxygen species (ROS). I
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zilpaterol mg The other type of cell death that occurs in
2022-07-12

The other type of cell death that occurs in activated T zilpaterol mg is caused by growth factor withdrawal following TCR-mediated activation, whereby most of the activated T cells die by apoptosis following the eradication of bacteria during an acute infection in order to reduce the level of cytok
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Fas ligand FasL the natural ligand of Fas
2022-07-12

Fas ligand (FasL), the natural ligand of Fas, can interact with Fas and thus induce cell apoptosis through the cascade of death signal in various cell types [8]. Additionally, Fas, which is a member of the tumor necrosis factor (TNF) receptor superfamily and death receptor family, is one kind of tra
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Most studies to date have focused
2022-07-12

Most studies to date have focused on the physiological functions of FPS in plants. As mentioned above, numerous factors affect FPS expression and FPS function. However, FPS enzymatic assays require radiolabeled substrate and thus detailed enzymatic characterizations of FPS, including substrate speci
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Methods br Results br Discussion SV
2022-07-12

Methods Results Discussion SV exocytosis from excitatory boutons is more sensitive to inhibition by isoflurane than exocytosis from inhibitory boutons,4, 31 but the mechanism(s) of this synaptic selectivity is unknown. Although P/Q-type VGCCs contributed quantitatively more to SV exocytosis t
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The organ culture method has
2022-07-12

The organ culture method has previously shown to be a suitable model for investigations of receptor upregulation on vascular smooth muscle cells (Adner et al., 1996). In our study, the organ culture method was applied in order to examine whether LPS from P.g. was capable of altering the gene express
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br Introduction Erythropoietin EPO is
2022-07-12

Introduction Erythropoietin (EPO) is a glycoprotein hormone and the principal stimulator of erythropoiesis (Jelkmann, 2011). EPO promotes the proliferation and differentiation of red blood cells, which is important for oxygen transport. Low EPO levels in blood cause anemia; however, excessive lev
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Describing histone acetylation machinery in rivulus will pro
2022-07-12

Describing histone acetylation machinery in rivulus will provide a basis for understanding the role of epigenetic mechanisms in mediating phenotypic variation, by guiding both phenotypic flexibility in adults and developmental plasticity in young. Together with its biological characteristics, rivulu
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Electrochemical techniques have attracted broad attention fo
2022-07-12

Electrochemical techniques have attracted broad attention for their outstanding advantages, such as satisfactory sensitivity and convenient operation. Nowadays, nucleic Donitriptan hydrochloride mg nanostructures such as DNA tetrahedron structure, nucleic acid-mimicking structure, exhibit noticeabl
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