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br Materials and methods br Results br Discussion
2018-11-12
Materials and methods Results Discussion The roles of endogenous stem/progenitor D-Luciferin in adult pancreatic tissue homeostasis, acute/chronic injury response and tumor initiation remain uncertain. However, it is now clear that a subset of pancreatic duct cells are capable of initiatin
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br Macrophage roles in cardiac injury responses While cTMs m
2018-11-12
Macrophage roles in cardiac injury responses While cTMs may play an important role in cardiac homeostasis, they are likely to be amongst the first cell types to react to cardiac tissue damage. Following injury, a robust inflammatory response involves secretion of various cytokines and infiltratio
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br Results The Hot Start experience and outcomes
2018-11-12
Results The Hot Start experience and outcomes were embodied in established and conceived infrastructure provided by its membership. This was both as originally proposed and subsequently informed and amended in the course of operational experience as follows. Discussion The EBiSC Hot Start yie
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br Materials and methods br Author
2018-11-12
Materials and methods Author disclosure statement 5. Acknowledgments This work was supported by the UK Medical Research Council grants G0701172 and G0801061. We thank Dr. Yacoub Khalaf, director of the Assisted Conception Unit of Guy\'s and St. Thomas\' NHS Foundation Trust and his staff fo
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tsh receptor To gain greater insight into the broad applicab
2018-11-09
To gain greater insight into the broad applicability for cell delivery, HAMC was investigated for the delivery of adult mouse NSCs (Morshead et al., 1994) to the brain. Significantly more cells were observed when delivered in HAMC versus artificial cerebrospinal fluid (aCSF) controls. Moreover, the
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Elevated SHH signaling in the dorsal
2018-11-09
Elevated SHH signaling in the dorsal V-SVZ regulates the production of oligodendrocyte progenitor cells in the corpus callosum while SHH signaling in the ventral V-SVZ controls the production of specific neuron subtypes destined for the OB (Tong et al., 2015). We previously observed that PTC deletio
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Here we identified and characterized
2018-11-09
Here, we identified and characterized MM cell subpopulations in vitro based on their increased endogenous expression of SOX2 and OCT4 driving a reporter (EGFP) (Hotta et al., 2009; Tang et al., 2015). We demonstrate these GSK461364 to have different properties with respect to chemoresistance, and t
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br Deposition of MgSe thin films MgSe thin solid films
2018-11-09
Deposition of MgSe thin films MgSe thin solid films were prepared using the versatile spray pyrolysis technique, which is simple and economic as compared to the MBE and MOCVD methods. The properties of the film can be controlled by adjusting the preparative parameters such as substrate temperatur
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br Methods br Results br
2018-11-09
Methods Results Discussion These findings support the life course model of a “sensitive period” during early life, in which factors during childhood influence health in the medium term (Ben-Shlomo et al., 2014). This type of model suggests that effects during this early window are long-last
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To illustrate consider how a
2018-11-09
To illustrate, consider how a young black man may experience his blackness when he is home with family and friends compared to if he is pulled over by the police for a minor traffic infraction. In this example, there may be neutral or positive psychosocial import of being black when with family and
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One of our most intriguing findings
2018-11-09
One of our most intriguing findings in the present study is that decreased goblet cell differentiation and mucus production were associated with severe inflammation in response to DSS in Adam17Mx1-Cre+ mice. Complete knockout of the Adam17 gene displays multiple pathological changes in several organ
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br Methods br Results The characteristics of the children in
2018-11-09
Methods Results The characteristics of the 313 children in the study are shown in Table 1. There were nearly equal numbers of girls and boys. Over 60% (194/313) of the children were stunted. A summary heatmap of the top fifty serum metabolites by HAZ is shown in Fig. 1. Serum amino MM-102 and
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In this context it is
2018-11-09
In this context, it is interesting to note that the impact of the cellular response associated with the β-catenin co-factor BCL9/9L may be context-dependent. Indeed, in the mouse, ablation of Bcl9/9l in the intestinal epithelium abrogates the expression of genes related to epithelial–mesenchymal tra
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br Author s Contributions br Funding Sources br Acknowledgem
2018-11-09
Author\'s Contributions Funding Sources Acknowledgements Introduction First isolated in 1947 from the blood of a Rhesus monkey in the Zika forest, Uganda (Dick et al., 1952), Zika virus (ZIKV) was recently declared a global public health emergency by WHO (Heymann et al., 2016). After dec
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We have previously reported the CM chip that enables precise
2018-11-09
We have previously reported the CM chip that enables precise estimation of rare cell counts in blood including spiked-in cultured cancer green (Yatsushiro et al., 2010; Yamamura et al., 2012). Although the CM chip produced excellent results in a preclinical study, we considered that precise enumera
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