• br Author Contributions br Disclosure br Acknowledgements

  2018-10-23

  

  Author Contributions Disclosure Acknowledgements We are grateful to J. De Rijck for critical reading and thank P. Van de Velde, B. Vanremoortel and NJ. Van der Veeken for their technical assistance. Viral vector production was performed at the Leuven Viral Vector Core. LEDGINs were synthesi

• br Materials and Methods br Results br

  2018-10-23

  

  Materials and Methods Results Discussion Until recently, many internal organs were believed to be sterile environments. Recent studies have however changed that view, showing that even healthy placentas consistently harbor microbial communities (Aagaard et al., 2014). This study serves to s

• However one might question whether effective compounds that

  2018-10-23

  

  However, one might question whether effective compounds that do not bind to the C-terminal domain of PrP or that have other molecular targets besides PrP () will be excluded from this virtual screening. In the first case, docking with at least the 90–231 domain of the prion protein will prove useful

• ceramide kinase br Detection of cancer by analysis

  2018-10-23

  

  Detection of cancer by analysis of circulating cell-free DNA (cfDNA) has received enormous attention over the past years (). cfDNA is released into the blood circulation by apoptotic and necrotic cells, and cancer patients have increased concentrations of cfDNA (). With the development of novel te

• CD also known as Basigin or EMMPRIN is

  2018-10-23

  

  CD147, also known as Basigin or EMMPRIN, is a highly glycosylated immunoglobulin superfamily protein. Under physiological conditions, this transmembrane protein is widely expressed and plays fundamental roles in various hematopoietic and non-hematopoietic cell lineages (Fok et al., 2014; Hahn et al.

• Until now no valid prognostic

  2018-10-23

  

  Until now, no valid prognostic biomarkers for GC chemotherapy have been established, although several potential molecular predictors of recurrence risk and chemotherapy benefit have been investigated (e.g., Ki-67, TS, TP, ERCC1, p21, and immune cell infiltration) (Jiang et al., 2016; Kwon et al., 20

• br Isolation of extracellular vesicles

  2018-10-23

  

  Isolation of extracellular vesicles and vesicle-free secretome Three biological replicates of P. aeruginosa PAO001 and FCP001 were obtained from mid-exponential growth phase cultures (OD600 of 0.6). Extracellular vesicles were concentrated using a Centricon Plus-70 filter (>100kDa) and pelleted b

• Desflurane concentrations in arterial blood samples were ana

  2018-10-23

  

  Desflurane concentrations in arterial blood samples were analyzed by Micropore Membrane Inlet Mass Spectrometry (MMIMS). Data on arterial blood desflurane during uptake and elimination are displayed in Fig. 3. The infusion of MCh induced bronchoconstriction and impaired arterial oxygenation did not

• Figs and indicate the SEM

  2018-10-23

  

  Figs. 9 and 10 indicate the SEM test for concrete samples made with 300kg/m3 of cement using drinking water and treated wastewater, respectively. The Scanning Electron Microscopy (SEM) images of concrete sample with 300kg/m3 of cement(B300) which was made of treated wastewater (Figs. 9 and 10) pres

• In the same study values for detonation pressure P and

  2018-10-22

  

  In the same study, values for detonation pressure (P) and velocity of detonation (VoD) were calculated using CHEETAH 2.0 thermochemical code. Heats of formation, which are required input for CHEETAH, were estimated using the empirical method of Keshavarz [68] and compared with the data for NTO, TATB

• Alumna Rosa Yo tengo una pregunta o sea

  2018-10-22

  

  Alumna Rosa: Yo tengo una pregunta, o sea, ¿qué significa ser feminista? O sea, si simplemente es estar de acuerdo con todas las causas por las que luchan o realmente es ser activista de cierta forma. Porque varios de aquí, no quiero hablar de ellos, pero pues serían feministas porque están a favor

• br Declaration of interest br Ethical approval br Informed

  2018-10-22

  

  Declaration of interest Ethical approval Informed consent Acknowledgments The present study was funded by the Institute Of Medical Genetics College Of Life Science, Sichuan University, China. Introduction With the advancement of technologies, laboratory medicine and the need of routi

• This practice was reinforced by the promulgation of

  2018-10-22

  

  This practice was reinforced by the promulgation of the Law on Protection of Cultural Relics in 2002, although the historical blocks, building complex, towns, and villages are redefined as historical urban areas, historical villages, and historical towns, respectively. In August 2008, the specifie

• Conclusions Three observations can be concluded

  2018-10-22

  

  Conclusions Three observations can be concluded from the success and deficiencies of the QPC workshop. The first one is that material and fabrication constraints have to be precisely modeled before the design stage. An in-depth study of the material and fabrication limitation is the key factor for

• br Reflective roof strategy slowing down the

  2018-10-22

  

  Reflective roof strategy (slowing down the heat transfer into a building) Studies estimate that about 60% of urban areas are covered by roofs and pavements (Akbari et al., 2008). This figure continues to increase, given that 50% of the world׳s population are currently found in urban regions. This

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