• In order to analyze and identify

  2018-11-12

  

  In order to analyze and identify the obtained mineral, additional Raman spectroscopy was performed (Putnis, 1992). It is known that calcium phosphate minerals show a characteristic peak at 960cm (Koutsopoulos, 2002; Sauer et al., 1994). All of the samples analyzed in the present study showed a stron

• In our model DNA damage forces

  2018-11-12

  

  In our model, DNA damage forces cells into cellular senescence, whereas ATM-dependent and p53-antagonized cytokine secretion activates BMP2/JAK-STAT signaling and stimulates the differentiation process in a progressive feed-forward manner. This senescent state is very different from the GFAP-associa

• br Results We next sought

  2018-11-12

  

  Results We next sought to look at the correlation between the methylation and expression levels of each somatic cell and the iPSCs that were generated from it. We looked at the methylation status for CpG island or nonisland CpG promoters in the four expression groups that we generated previously

• Why ectopic BRIGHT knockdown was capable of stimulating

  2018-11-12

  

  Why ectopic BRIGHT knockdown was capable of stimulating reprogramming by the conventional 4F method but not singularly is unclear. While BRIGHT levels in MEFs are modest compared to hematopoietic tissues (Webb et al., 2011), we were only able to achieve ∼75% reduction in transcript levels (Figure S1

• br Conclusions br Author contributions

  2018-11-12

  

  Conclusions Author contributions Conflicts of interest Acknowledgments Introduction Self-renewal is an integrated proliferation control that maintains undifferentiated states of stem cells. The integrated control is achieved by multilayered regulatory networks involving complex interp

• br Materials and methods br Results br Discussion

  2018-11-12

  

  Materials and methods Results Discussion The roles of endogenous stem/progenitor D-Luciferin in adult pancreatic tissue homeostasis, acute/chronic injury response and tumor initiation remain uncertain. However, it is now clear that a subset of pancreatic duct cells are capable of initiatin

• br Macrophage roles in cardiac injury responses While cTMs m

  2018-11-12

  

  Macrophage roles in cardiac injury responses While cTMs may play an important role in cardiac homeostasis, they are likely to be amongst the first cell types to react to cardiac tissue damage. Following injury, a robust inflammatory response involves secretion of various cytokines and infiltratio

• br Results The Hot Start experience and outcomes

  2018-11-12

  

  Results The Hot Start experience and outcomes were embodied in established and conceived infrastructure provided by its membership. This was both as originally proposed and subsequently informed and amended in the course of operational experience as follows. Discussion The EBiSC Hot Start yie

• br Materials and methods br Author

  2018-11-12

  

  Materials and methods Author disclosure statement 5. Acknowledgments This work was supported by the UK Medical Research Council grants G0701172 and G0801061. We thank Dr. Yacoub Khalaf, director of the Assisted Conception Unit of Guy\'s and St. Thomas\' NHS Foundation Trust and his staff fo

• tsh receptor To gain greater insight into the broad applicab

  2018-11-09

  

  To gain greater insight into the broad applicability for cell delivery, HAMC was investigated for the delivery of adult mouse NSCs (Morshead et al., 1994) to the brain. Significantly more cells were observed when delivered in HAMC versus artificial cerebrospinal fluid (aCSF) controls. Moreover, the

• Elevated SHH signaling in the dorsal

  2018-11-09

  

  Elevated SHH signaling in the dorsal V-SVZ regulates the production of oligodendrocyte progenitor cells in the corpus callosum while SHH signaling in the ventral V-SVZ controls the production of specific neuron subtypes destined for the OB (Tong et al., 2015). We previously observed that PTC deletio

• Here we identified and characterized

  2018-11-09

  

  Here, we identified and characterized MM cell subpopulations in vitro based on their increased endogenous expression of SOX2 and OCT4 driving a reporter (EGFP) (Hotta et al., 2009; Tang et al., 2015). We demonstrate these GSK461364 to have different properties with respect to chemoresistance, and t

• br Deposition of MgSe thin films MgSe thin solid films

  2018-11-09

  

  Deposition of MgSe thin films MgSe thin solid films were prepared using the versatile spray pyrolysis technique, which is simple and economic as compared to the MBE and MOCVD methods. The properties of the film can be controlled by adjusting the preparative parameters such as substrate temperatur

• br Methods br Results br

  2018-11-09

  

  Methods Results Discussion These findings support the life course model of a “sensitive period” during early life, in which factors during childhood influence health in the medium term (Ben-Shlomo et al., 2014). This type of model suggests that effects during this early window are long-last

• To illustrate consider how a

  2018-11-09

  

  To illustrate, consider how a young black man may experience his blackness when he is home with family and friends compared to if he is pulled over by the police for a minor traffic infraction. In this example, there may be neutral or positive psychosocial import of being black when with family and

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