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There are several limitations that should be
2018-10-24
There are several limitations that should be considered when interpreting the results of this review. First, given the search strategy, we were unable to identify unpublished studies or studies that were not published in indexed journals. Studies in languages other than English were also not includ
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More importantly as social and
2018-10-24
More importantly, as social and family structures have changed rapidly, the living arrangements of older people are perceived as a dynamic process rather than a static status, which in turn may influence the adaptability to new circumstances, and thereby upon older people\'s mortality (Li and Li, 20
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The first step in estimating a relation between
2018-10-23
The first step in estimating a relation between savings and the exchange rate is to correct the exchange rate using the Balassa-Samuelson effect, according to which the exchange rate must reflect the productivity gap between each country\'s tradable and non-tradable goods sectors. To adjust a count
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br A selective review of literature Mincerian equations deco
2018-10-23
A selective review of literature: Mincerian equations, decomposition of income distribution and occupations In the 20th century, Schultz (1961) and Ben-Porath (1967) formulated, despite the lack of theoretical strictness, the relation between education and income. However, the debates and the emp
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This article is presented in six sections In
2018-10-23
This article is presented in six sections. In the following section, we provide some background on currency internationalization and the discussions on the use of vehicle currencies. Then, in Section 3, we describe our database and the methodology. Section 4 describes in which currencies the Brazili
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Secondly the pyrazinamide concentrations were approximately
2018-10-23
Secondly, the pyrazinamide concentrations were approximately similar to those in plasma. However, this is substantially lower than the concentrations associated with effective microbial kill at the site of infection. In pulmonary epithelial lining fluid, pyrazinamide is concentrated 17–22-fold, comp
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From a translational standpoint TSCM cells emerge
2018-10-23
From a translational standpoint, TSCM topoisomerase inhibitors emerge as most promising population for immunotherapy. In this regard, recent reports which indicate that the efficacy of CAR T cells might be based on their acquisition of a TSCM cell phenotype are highly encouraging (Yang et al., 2014
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br Discussion br In Conclusion
2018-10-23
Discussion In Conclusion Declaration of Interests Authors\' Contributions Role of the Funding Source Introduction It is likely that the genetic heterogeneity of the schizophrenia-related psychoses will be pertinent to the development of optimal person-specific treatments. We teste
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br Materials and Methods br
2018-10-23
Materials and Methods Results Discussion The prophylactic tolerance protocol entails the administration of immunosuppressive drugs. Rapamycin is an mTOR inhibitor approved for immunosuppression in organ transplantation (and is commonly used in children (Ganschow et al., 2013)) and has poten
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On the basis of our genetic findings that hexokinase HK
2018-10-23
On the basis of our genetic findings that hexokinase 2 (HK2)-mediated aerobic glycolysis, known as the Warburg effect, drives prostate tumor growth in xenograft model bearing /p53-deficient murine or human prostate cancer VE-822 (Wang et al., 2014), we designed preclinical studies to determine the
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br Author Contributions br Disclosure br Acknowledgements
2018-10-23
Author Contributions Disclosure Acknowledgements We are grateful to J. De Rijck for critical reading and thank P. Van de Velde, B. Vanremoortel and NJ. Van der Veeken for their technical assistance. Viral vector production was performed at the Leuven Viral Vector Core. LEDGINs were synthesi
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br Materials and Methods br Results br
2018-10-23
Materials and Methods Results Discussion Until recently, many internal organs were believed to be sterile environments. Recent studies have however changed that view, showing that even healthy placentas consistently harbor microbial communities (Aagaard et al., 2014). This study serves to s
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However one might question whether effective compounds that
2018-10-23
However, one might question whether effective compounds that do not bind to the C-terminal domain of PrP or that have other molecular targets besides PrP () will be excluded from this virtual screening. In the first case, docking with at least the 90–231 domain of the prion protein will prove useful
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ceramide kinase br Detection of cancer by analysis
2018-10-23
Detection of cancer by analysis of circulating cell-free DNA (cfDNA) has received enormous attention over the past years (). cfDNA is released into the blood circulation by apoptotic and necrotic cells, and cancer patients have increased concentrations of cfDNA (). With the development of novel te
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CD also known as Basigin or EMMPRIN is
2018-10-23
CD147, also known as Basigin or EMMPRIN, is a highly glycosylated immunoglobulin superfamily protein. Under physiological conditions, this transmembrane protein is widely expressed and plays fundamental roles in various hematopoietic and non-hematopoietic cell lineages (Fok et al., 2014; Hahn et al.
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