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br Conclusions In summary aromatase mRNA expression
2024-08-15
Conclusions In summary, aromatase mRNA expression in the Myosmine of A. leptorhynchus shows a similar distribution pattern as seen in other teleosts with expression detected in the forebrain and the pituitary gland. The lack of aromatase mRNA expression in the midbrain and hindbrain of A. leptor
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In view of the ubiquitous distribution of the
2024-08-15
In view of the ubiquitous distribution of the arachidonate 12S-lipoxygenase isoforms and the variety of cellular reactions influenced by the resulting arachidonate metabolites, these products widely play important roles in many biological systems. The development of new type-specific inhibitors of t
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Outro grupo de trabalho analisou pares de g meos
2024-08-15
Outro grupo de trabalho analisou 8.503 pares de gêmeos dinamarqueses de meia‐idade (RSL3 de cognição comparados com os que não sofreram qualquer intervenção, no entanto os autores consideram a diferença como um efeito de tamanho negligenciável. Na análise intrapares o gêmeo exposto à cirurgia tinha
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Aminoallyl-dUTP With regard to the correlation between rearr
2024-08-15
With regard to the correlation between -rearrangements and thromboembolic events, Zer et al. reported a VTE rate of 36% in a cohort of 98 patients with ALK-positive NSCLC. Of note, VTE was also associated with shorter overall survival (HR: 5.71, =0.01) . Only few others have investigated NSCLC drive
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Accumulating evidence suggest that patients
2024-08-15
Accumulating evidence suggest that patients with advanced -positive NSCLC are at increased risk of VTE or coagulation disorders during the course of their disease, indicating that cancer genotype might play a role in the occurrence of cancer-related thromboembolism . Here we report the case of a pat
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To date defining the prognostic impact
2024-08-15
To date, defining the prognostic impact of molecular drivers of early-stage NSCLC has been challenging due to the relative rarity of these subsets and the redefinition of comparator arms over time as understanding of the molecular drivers of NSCLC evolved. Indeed, use of molecularly heterogeneous co
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Herein we employ an adapted targeted quantitative
2024-08-15
Herein we employ an adapted targeted quantitative proteomic isotope dilution method, developed in our laboratory [[18], [19], [20], [21]], to quantify membrane transporters in fresh lung from five donors, in four immortalized human lung cell lines and in three control cell lines. We quantify twelve
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Until now the molecular interactions of Tmod or Lmod with
2024-08-14
Until now, the molecular interactions of Tmod or Lmod with Meropenem had been assessed in pyrene-actin polymerization assays [13], [23], [27], [28], [44], [45] or directly measured using non-denaturing polyacrylamide gel-electrophoresis (for Tmod isoforms only [23]), ITC (for Tmod1 and Lmod2) [43],
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br Methodology In this paper mechanical properties
2024-08-14
Methodology In this paper, mechanical properties of G-actin are examined. To do so, three different external tensile loads are exerted to the protein. As illustrated in Fig. 1, Arp2/3 complex binds to the one sides of mother hypoxia inducible factor and leads to the growth of a new daughter filam
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guanylyl cyclase PL for actin in vitro showed that its
2024-08-14
PL for guanylyl cyclase in vitro showed that its profiles, including particular peak and intensity, could determine the length and thickness of an actin filament. Furthermore, we investigated if the PL intensity peak at approximately 340 nm can also be originated from another cytoskeleton filament,
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The obtained results indicate that even when
2024-08-14
The obtained results indicate that even when the impairment of the same forms of memory are present, amnesia can develop in different ways. Impairment of memory reconsolidation in the conditioned food aversion model through both the serotonin receptor antagonist and the antagonist of NMDA glutamate
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br Concluding remarks It is clear
2024-08-14
Concluding remarks It is clear that a disordered l-arginine homeostasis by changes in arginase, NOS and ADMA activity and expression, is not only vital in the chronic airway diseases, NSC228155 and COPD, but also seems to play an important role in many co-morbidities. Unknown, however, is whether
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In the early s in addition
2024-08-14
In the early 2000s, in addition to above-mentioned plant derived compounds, several peptide fragments from protein sources (e.g. gelatin, egg yolk, meat, fish, chicken, legumes) have been also confirmed as potential natural antioxidants and extensive studies about bioactive peptides have been condu
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We further conducted stratified analyses to observe changes
2024-08-14
We further conducted stratified analyses to observe changes in enzyme levels across the periods by subgroups. Fig. 1 shows the changes in GPx levels by subgroups of age, sex, and smoking status. In all participants, GPx levels decreased when air pollution levels declined but increased after the Olym
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Protein microarrays represent just one of a variety of
2024-08-14
Protein microarrays represent just one of a variety of experimental approaches that can be used to generate datasets of relevance to pathway mapping. Other approaches include protein BH3I-1 synthesis profiling techniques, such as antibody arrays [29], tissue arrays [30] and 2-dimensional gel electr
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